Calcitriol
货号：
71820-10mg 基本售价：
6664.0 元 规格：
10 mg
产品信息
概述| 货号 | 71820-10mg |
| 描述 | Calcitriol (1α,25-dihydroxy Vitamin D3) is synthesized from 7-dehydrocholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin.1 Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy Vitamin D3, the principal circulating form of Vitamin D. A second, tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors.2 The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium, and to increase the mineralization of bone via the direct stimulation of osteoblasts.3 |
| 别名 | 1α,25-dihydroxy Vitamin D3; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kumar, R. Metabolism of 1,25-dihydroxyvitamin D3. Physiol. Rev. 64(2), 478-505 (1984).
2.Bikle, D.D.,Gee, E.,Halloran, B., et al. Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease. J. Clin. Invest. 74(6), 1966-1971 (1984).
3.Portale, A.A.,Halloran, B.P., and Morris, R.C., Jr. Physiologic regulation of the serum concentration of 1,25-dihydroxyvitamin D by phosphorus in normal men. Journal of Clinical Investigation 83, 1494-1499 (1989).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 416.6 |
| 分子式 | C27H44O3 |
| CAS号 | 32222-06-3 |
| 稳定性 | ≥ 2 years |
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