PPARγ FL (human recombinant from E. coli)
货号：
61700-50ug 基本售价：
6650.0 元 规格：
50 ug
产品信息
概述| 货号 | 61700-50ug |
| 描述 | Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor family of ligand activated transcription factors that heterodimerizes with retinoic acid-like receptors to regulate gene expression and differentiation.1 The PPAR family of nuclear hormone receptors consists of three subtypes encoded by separate genes: PPARα, PPARδ (also referred to as hNUC1, PPARβ, or FAAR), and PPARγ. Among them PPARγ is the most widely studied and has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis, and cancer.2 PPARγ is primarily expressed in adipose tissue and to a lesser extent in the colon, immune system, and the retina.3 PPARγ FL (human recombinant from E. coli) purity was determined using gel electrophoresis followed by coomassie staining. |
| 别名 | Peroxisome Proliferator-activated Receptor γ Full Length; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kersten, S.,Desvergne, B., and Wahli, W. Roles of PPARs in health and disease. Nature 405, 421-424 (2000).
2.Vidal-Puig, A.,Jimenez-Linan, M.,Lowell, B.B., et al. Regulation of PPAR γ gene expression by nutrition and obesity in rodents. Journal of Clinical Investigation 97, 2553-2561 (1996).
3.Clark, R.B. The role of PPARs in inflammation and immunity. Journal of Leukocyte Biology 71, 388-400 (2002).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥80% estimated by SDS-PAGE |
| 稳定性 | ≥ 6 months |
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