Altertoxin I
货号：
21129-1mg 基本售价：
6650.0 元 规格：
1 mg
产品信息
概述| 货号 | 21129-1mg |
| 描述 | Altertoxin I is a natural mycotoxin first isolated from fungi of the genus Alternaria. It is a hydroxyperylenequinone that shows mutagenic activity against S. typhimurium and inhibits human topoisomerase II and bacterial gyrase.1,2 Altertoxin I completely inhibits replication of HIV-1 virus at 2.2 µM in a cell-based assay.3 |
| 别名 | Dihydroalterperylenol; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Jarolim, K.,Del Favero, G.,Ellmer, D., et al. Dual effectiveness of Alternaria but not Fusarium mycotoxins against human topoisomerase II and bacterial gyrase. Arch. Toxicol. 91(4), 2007-2016 (2016).
2.Stack, M.E. and Prival, M.J. Mutagenicity of the Alternaria metabolites altertoxins I, II, and III. Appl. Environ. Microbiol. 52(4), 718-722 (1986).
3.Bashyal, B.P.,Wellensiek, B.P.,Ramakrishnan, R., et al. Altertoxins with potent anti-HIV activity from Alternaria tenuissima QUE1Se, a fungal endophyte of Quercus emoryi. Bioorg. Med. Chem. 22(21), 6112-6116 (2014).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 352.3 |
| 分子式 | C20H16O6 |
| CAS号 | 56258-32-3 |
| 稳定性 | ≥ 2 years |
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