9(R)-PAHSA
货号:
18022-1mg 基本售价:
6622.0 元 规格:
1 mg
产品信息
概述货号 | 18022-1mg |
描述 | 9(R)-PAHSA is a stereoisomer of 9-PAHSA (Item No. 17037), an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).1 9-PAHSA is a FAHFA in which palmitic acid (Item No. 10006627) is esterified to 9-hydroxy stearic acid. 9(R)-PAHSA is the predominant form that accumulates in adipose tissues in AG4OX mice, which overexpress Glut4 specifically in adipose tissue.2 Also, cell lines favor the production of 9(R)-PAHSA, and carboxyl ester lipase selectively hydrolyzes 9(S)-PAHSA (Item No. 18023). |
性能供应商 | Cayman |
应用文献 |
1.Yore, M.M.,Syed, I.,Moraes-Vieira, P.M., et al. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell. 159(2), 318-332 (2014). 2.Nelson, A.T.,Kolar, M.J.,Chu, Q., et al. Stereochemistry of endogenous palmitic acid ester of 9-hydroxystearic acid and relevance of absolute configuration to regulation. J. Am. Chem. Soc. 139(13), 4943-4947 (2017).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 538.9 |
分子式 | C34H66O4 |
稳定性 | ≥ 1 year |
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