Compound C108
货号：
9002951-5mg 基本售价：
6608.0 元 规格：
5 mg
产品信息
概述| 货号 | 9002951-5mg |
| 描述 | Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation.1 In a mouse xenograft model of breast cancer, compound C108 (1 µM for 24 hours) reduces the proportion of tumor-initiating cells approximately 10-fold compared with untreated cells. In MDA-MB-453 cells, and in the patient-derived xenograft cell line MAXF 401, it diminishes mammosphere formation. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gupta, N.,Badeaux, M.,Liu, Y., et al. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc. Natl. Acad. Sci. USA 114(5), 1033-1038 (2017).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 270.3 |
| 分子式 | C15H14N2O3 |
| CAS号 | 15533-09-2 |
| 稳定性 | ≥ 2 years |
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