Isobavachalcone
货号：
19873-50mg 基本售价：
6608.0 元 规格：
50 mg
产品信息
概述| 货号 | 19873-50mg |
| 描述 | Isobavachalcone is a natural chalcone first isolated from P. corylifolia that displays antibacterial, antifungal, anticancer, anti-reverse transcriptase, antitubercular, and antioxidant activities in various research models.1 It can inhibit the growth of MGC803 gastric cancer cells by regulating the protein expression of caspase-3, Bcl-2, and Bax and by inhibiting Akt and ERK signaling pathways.2 Isobavachalcone has also been shown to inhibit oligomerization and fibrillization of Aβ42 in an SH-SY5Y cell model of Aβ42 aggregation.3 |
| 别名 | Corylifolinin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kuete, V., and Sandjo, L.P. Isobavachalcone: An overview. Chin.J.Integr.Med. 18(7), 543-547 (2012).
2.Jin, X., and Shi, Y. Isobavachalcone induces the apoptosis of gastric cancer cells via inhibition of the Akt and Erk pathways. Exp.Ther.Med. 11(2), 403-408 (2016).
3.Chen, X.,Yang, Y., and Zhang, Y. Isobavachalcone and bavachinin from Psoraleae Fructus modulate Aβ42 aggregation process through different mechanisms in vitro. FEBS Lett. 587(18), 29350-29355 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 324.4 |
| 分子式 | C20H20O4 |
| CAS号 | 20784-50-3 |
| 稳定性 | ≥ 2 years |
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