I-SAP
货号:
19021-1mg 基本售价:
6608.0 元 规格:
1 mg
产品信息
概述货号 | 19021-1mg |
描述 | I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and 490 pM at pH 6.5.1 |
别名 | Iodophenyl sulfonyl amino pinane Thromboxane A2;Iodophenyl sulfonyl amino pinane TXA2; |
性能供应商 | Cayman |
应用文献 |
1.Naka, M.,Mais, D.E.,Morinelli, T.A., et al. 7-[(1R,2S,3S,5R)-6,6-Dimethyl-3-(4-iodobenzenesulfonylamino)bicyclo[3.1.1]hept-2-yl]-5(Z)-heptenoic acid: A novel high-affinity radiolabeled antagonist for platelet thromboxane A2/prostaglandin H2 receptors. Journal of Pharmacology and Experimental Therapeutics 262, 632-637 (1992).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 531.4 |
分子式 | C22H30INO4S |
CAS号 | 133538-58-6 |
稳定性 | ≥ 2 years |
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