Necrox-5 (methanesulfonate)
货号：
17278-10mg 基本售价：
6608.0 元 规格：
10 mg
产品信息
概述| 货号 | 17278-10mg |
| 描述 | Necrox-5 is a cell permeable inhibitor of necrosis that also demonstrates strong mitochondrial reactive oxygen species and ONOO- scavenging activity.1 It predominantly localizes in mitochondria, selectively blocking oxidative stress-induced necrotic cell death (0.1 μM necrox-5 inhibits ~50% cell death in H9C2 cells exposed to 400 μM t-BHP).1 This compound has been shown to protect cells from oxidative stress, hypoxia, and cold shock in vitro, as well as carbon tetrachloride-induced liver injury and chronic liver fibrosis in rodent models.1 |
| 别名 | Necrosis Inhibitor 5;NecroX-5; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kim, H.J.,Koo, S.Y.,Ahn, B.H., et al. NecroX as a novel class of mitochondrial reactive oxygen species and ONOO- scavenger. Archives of Pharmacal Research 33(11), 1813-1823 (2010).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 645.8 |
| 分子式 | C25H31N3O3S • 2CH4O3S |
| CAS号 | 1383718-29-3 |
| 稳定性 | ≥ 2 years |
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