| 货号 | 14530-10mg |
| 描述 | Bicyclo prostaglandin E2 (bicyclo PGE2) is a stable breakdown product of PGE2 (Item No. 14010) and 13,14-dihydro-15-keto PGE2 (Item No. 14650). Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2 found in human plasma at a median level of 20-25 pg/ml.1,2 Due to the inherent instability of 13,14-dihydro-15-keto PGE2, it is advisable to quantify it as bicyclo PGE2 to estimate PGE2 biosynthesis or metabolism in vivo.3,4 |
| 别名 | Bicyclo PGE2; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Hamberg, M. and Samuelsson, B. On the metabolism of prostaglandins E1 and E2 in man. The Journal of Biological Chemisty 246, 6713-6721 (1971). 2.Leonhardt, A.,Krauss, M.,Gieler, U., et al. In vivo formation of prostaglandin E1 and prostaglandin E2 in atopic dermatitis. British Journal of Dermatology 136, 337-340 (1997). 3.Murphy, R.C. and Fitzgerald, G.A. Current approaches to estimation of eicosanoid formation in vivo. Advances in Prostaglandin, Thromboxane, and Leukotriene Research 22, 341-348 (1994). 4.Granström, E.,Hamberg, M.,Hansson, G., et al. Chemical instability of 15-keto-13,14-dihydro-PGE2: The reason for low assay reliability. Prostaglandins 19, 933-945 (1980). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 334.5 |
| 分子式 | C20H30O4 |
| CAS号 | 74158-09-1 |
| 稳定性 | ≥ 2 years |
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