9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (potassium salt)
货号:
14430-10mg 基本售价:
6608.0 元 规格:
10 mg
产品信息
概述货号 | 14430-10mg |
描述 | 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (metenprost) is a potent analog of PGE2 with an extended half-life in vivo. In combination with various other PG derivatives, metenprost results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of metenprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy.1 This PG mixture is ineffective on monkeys in their third trimester of pregnancy.1 Metenprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.1,2 |
别名 | Metenprost potassium;9-deoxy-9-methylene-16,16-dimethyl PGE2 (potassium salt);U-46785b; |
性能供应商 | Cayman |
应用文献 |
1.Wilks, J.W. Pregnancy interception with a combination of prostaglandins: Studies in monkeys. Science 221, 1407-1409 (1983). 2.Bundy, G.L.,Kimball, F.A.,Robert, A., et al. Synthesis and biological activity of 9-deoxo-9-methylene and related prostaglandins. Advances in Prostaglandin and Thromboxane Research 6, 355-363 (1980).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 416.6 |
分子式 | C23H37O4 • K |
CAS号 | 122576-55-0 |
稳定性 | ≥ 6 months |
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