货号 | 2457-25 |
描述 | A potent ATR (ATM and Rad3-related) inhibitor (IC₅₀ = 25 nM). It also inhibits the activity of PI3Kα, mTOR and DNA-PKC with IC₅₀s of 170, 0.6 and 36 nM, respectively. ETP-46464 inhibits the restart of stalled replication forks and abrogates S phase arrest after exposure to hydroxyurea. |
供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | White solid |