Z-AEVD-FMK
货号：
14987-5mg 基本售价：
6552.0 元 规格：
5 mg
产品信息
概述| 货号 | 14987-5mg |
| 描述 | Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.1 At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.2 |
| 别名 | Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Park, S.J.,Wu, C.H.,Gordon, J.D., et al. Taxol induces caspase-10-dependent apoptosis. The Journal of Biological Chemisty 279(49), 51057-51067 (2004).
2.Milhas, D.,Cuvillier, O.,Therville, N., et al. Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis. The Journal of Biological Chemisty 280(20), 19836-19842 (2005).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 610.6 |
| 分子式 | C28H39FN4O10 |
| CAS号 | 1135688-47-9 |
| 稳定性 | ≥ 2 years |
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