Masitinib
货号：
13105-100mg 基本售价：
6552.0 元 规格：
100 mg
产品信息
概述| 货号 | 13105-100mg |
| 描述 | Masitinib is a potent and selective inhibitor of c-Kit (IC50 = 200 nM for human recombinant c-Kit), a receptor tyrosine kinase protein.1 It also inhibits PDGFRα and PDGFRβ (IC50s = 540 and 800 nM, respectively), and Lyn (IC50 = 510 nM). It has antiproliferative, antiangiogenic, and chemosensitizing properties.2 |
| 别名 | AB-1010; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Dubreuil, P.,Letard, S.,Ciufolini, M., et al. Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT. PLoS One 4(9), e7258 (2009).
2.Marech, I.,Patruno, R.,Zizzo, N., et al. Masitinib (AB1010), from canine tumor model to human clinical development: where we are? Crit. Rev. Oncol. Hematol. 91(1), 98-111 (2014).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 498.6 |
| 分子式 | C28H30N6OS |
| CAS号 | 790299-79-5 |
| 稳定性 | ≥ 2 years |
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