11-keto Fluprostenol
货号:
16783-10mg 基本售价:
6496.0 元 规格:
10 mg
产品信息
概述货号 | 16783-10mg |
描述 | 11-keto Fluprostenol is an analog of prostaglandin D2(PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor.1 Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1receptor.2 |
别名 | Fluprostenol Prostaglandin D2; |
性能供应商 | Cayman |
应用文献 |
1.Dukes, M.,Russell, W. and Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α. Nature 250, 330-331 (1974). 2.Monneret, G.,Cossette, C.,Gravel, S., et al. 15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils. Journal of Pharmacology and Experimental Therapeutics 304(1), 349-355 (2003).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 456.5 |
分子式 | C23H27F3O6 |
CAS号 | 62145-07-7 |
稳定性 | ≥ 2 years |
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