(+)-Cloprostenol isopropyl ester
货号：
10010016-10mg 基本售价：
6496.0 元 规格：
10 mg
产品信息
概述| 货号 | 10010016-10mg |
| 描述 | (+)-Cloprostenol is a synthetic analog of prostaglandin F2α(PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF2α in terminating pregnancy when given subcutaneously at a daily dose of 0.125 μg/kg in rats and hamsters, without the side effects associated with PGF2α.1 (+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 x 10-12 M.2 Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol. |
| 别名 | (+)-16-m-chlorophenoxy tetranor Prostaglandin F2α isopropyl ester; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Dukes, M.,Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α. Nature 250, 330-331 (1974).
2.Serrero, G., and Lepak, N.M. Prostaglandin F2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochemical and Biophysical Research Communications 233, 200-202 (1997).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 467 |
| 分子式 | C25H35ClO6 |
| CAS号 | 157283-66-4 |
| 稳定性 | ≥ 1 year |
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