CAY10648
货号:
9000549-10mg 基本售价:
6384.0 元 规格:
10 mg
产品信息
概述货号 | 9000549-10mg |
描述 | Prostaglandin D2(PGD2) evokes its effects through two receptors, DP1 and CRTH2/DP2. The activation of DP2 leads to eosinophil chemotaxis, activation, and degranulation as well as recruitment of basophils and lymphocytes and, as a result, is important in allergic inflammatory disease. CAY10648 is an intermediate used in the synthesis of potent DP2 receptor antagonists based on a novel spiro-indolinone compound.1 |
性能供应商 | Cayman |
应用文献 |
1.Crosignani, S.,Page, P.,Missotten, M., et al. Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases. Journal of Medicinal Chemistry 51, 2227-2243 (2008).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 350.8 |
分子式 | C17H19ClN2O4 |
CAS号 | 916048-02-7 |
稳定性 | ≥ 2 years |
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