Prostaglandin F2α isopropyl ester
货号:
16030-10mg 基本售价:
6384.0 元 规格:
10 mg
产品信息
概述货号 | 16030-10mg |
描述 | PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application in studies on intraocular pressure. The ester functionality is readily hydrolyzed in vivo to release the active compound PGF2α. When administered topically to the eyes of cynomolgus monkeys, a 5 µg dose reduces intraocular pressure by 68% after the fourth day of treatment.1 |
别名 | Dinoprost isopropyl ester;PGF2α isopropyl ester; |
性能供应商 | Cayman |
应用文献 |
1.Crawford, K.S. and Kaufman, P.L. Dose-related effects of prostaglandin F2α isopropyl ester on intraocular pressure, refraction, and pupil diameter in monkeys. Investigative Ophthalmology & Visual Science 32, 510-519 (1991).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 396.6 |
分子式 | C23H40O5 |
CAS号 | 53764-90-2 |
稳定性 | ≥ 2 years |
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