9-PAHSA 13C4
货号：
17725-1mg 基本售价：
6370.0 元 规格：
1 mg
产品信息
概述| 货号 | 17725-1mg |
| 描述 | Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.1 Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to a hydroxylated C-16 or C-18 lipid. 9-PAHSA (Item No. 17037) is a FAHFA in which palmitic acid is esterified to 9-hydroxy stearic acid. PAHSAs are the most abundant forms of FAHFA in serum as well as white and brown adipose tissues of glucose tolerant AG4OX mice, which overexpress Glut4 specifically in adipose tissue.1 9-PAHSA is the predominant isomer of PAHSA in wild type and AG4OX mice.1 It is found in humans and is reduced in the serum and adipose tissues of insulin-resistant humans.1 9-PAHSA improves glucose tolerance, stimulates insulin secretion, and has anti-inflammatory effects in mice.19-PAHSA13C4 is an isotopically enriched form of this polyunsaturated fatty acid with carbon-13 occurring at positions 1, 2, 3, and 4. It is intended for use as an internal standard for the quantification of 9-PAHSA by NMR or GC- or LC-mass spectrometry. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Yore, M.M.,Syed, I.,Moraes-Vieira, P.M., et al. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell. 159(2), 318-332 (2014).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 542.9 |
| 分子式 | C30[13C]4H66O4 |
| 稳定性 | ≥ 1 year |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
