Autotaxin Inhibitor Screening Assay Kit
货号:
700580-96Well 基本售价:
6300.0 元 规格:
96 wells
产品信息
概述货号 | 700580-96Well |
描述 | Autotaxin (ATX, Ectonucleotide Pyrophosphatase/Phosphodiesterase-2, ENPP-2, Lysophospholipase D) is a secreted lysophospholipase D that catalyzes the hydrolysis of lysophosphatidylcholine (LPC) to generate lysophosphatidic acid (LPA). LPA is a lipid mediator that activates G protein-coupled receptors and induces a variety of biological responses, such as neurogenesis, angiogenesis, smooth-muscle contraction, platelet aggregation, and wound healing. ATX-LPA signaling is involved in a range of pathologies including tumor progression and inflammation. Cayman’s Autotaxin Inhibitor Screening Assay provides a convenient method for screening human ATX inhibitors. ATX cleaves bis-(p-nitrophenyl) phosphate liberating p-nitrophenol, a yellow product that is measured at 405-415 nm. |
别名 | ATX Inhibitor Screening Assay Kit; |
性能供应商 | Cayman |
运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
稳定性 | ≥ 6 months |
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