| 货号 | 16663-5mg |
| 描述 | Chlortetracycline is an analog of tetracycline (Item No. 14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response.1,2,3,44-epi-Chlortetracycline is an epimer of chlortetracycline. |
| 别名 | 7-chloro-2-Naphthacenecarboxamide; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Elferink, J.G. and Deierkauf, M. Inhibition of polymorphonuclear leukocyte functions by chlortetracycline. Biochemical Pharmacology 33(22), 3667-3673 (1984). 2.Akunda, J.K.,Johnson, E.,Ahrens, F.A., et al. Chlortetracycline modulates acute phase response of ex vivo perfused pig livers, and inhibits TNF-α secretion by isolated Kupffer cells. Comparative Immunology, Microbiology and Infectious Diseases 24(2), 81-89 (2001). 3.Häyrinen-Immonen, R.,Sorsa, T.,Pettilä, J., et al. Effect of tetracyclines on collagenase activity in patients with recurrent aphthous ulcers. J.Oral Pathol.Med. 23(6), 269-272 (1994). 4.Rasmussen, B.,Noller, H.F.,Daubresse, G., et al. Molecular basis of tetracycline action: Identification of analogs whose primary target is not the bacterial ribosome. Antimicrobial Agents and Chemotherapy 35(11), 2306-2311 (1991). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 515.3 |
| 分子式 | C22H23ClN2O8 • HCl |
| CAS号 | 101342-45-4 |
| 稳定性 | ≥ 2 years |
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