TCS PIM-1 4a (50 MG)
货号：
3714/50 基本售价：
6236.2 元 规格：
50 mg
产品信息
概述| 货号 | 3714/50 |
| 别名 | (5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione; SMI-4a |
性能| 供应商 | Tocris |
| 生物活性 | Selective, ATP-competitive Pim kinase inhibitor (IC50 values are 24 and 100 nM for Pim-1 and Pim-2 respectively). Displays selectivity over a panel of ~50 other kinases tested. Exhibits cytotoxicity in PC3 prostate carcinoma cells in vitro(IC50 = 17 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 273.23 |
| 分子式 | C11H6F3NO2S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 438190-29-5 |
| 参考文献 | Xiaet al (2009) Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J.Med.Chem. 52 74. PMID: 19072652. |
