S 07662 (50 MG)
货号:
5188/50 基本售价:
6236.2 元 规格:
50 mg
产品信息
概述货号 | 5188/50 |
别名 | N-[(2-Methyl-3-benzofuranyl)methyl]-N'-(2-thienylmethyl)urea |
性能供应商 | Tocris |
生物活性 | Inverse agonist of the constitutive androstane receptor (CAR). Inhibits CAR activity via recruitment of nuclear receptor co-repressor (NCoR). Suppresses CITCO-induced CYP2B6 gene expression in human primary hepatocytes. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 300.38 |
分子式 | C16H16N2O2 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
参考文献 | Küblbecket al (2011) New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists. Mol.Pharm. 8 2424. PMID: 22044162. |