| 货号 | 5810/50 |
| 别名 | 4-Bromo-N-(4-bromophenyl)-3-[[(phen |
| 供应商 | Tocris |
| 生物活性 | High affinity RAD51 activator (Kd range = 48-107 nM, value depends on cofactors present). Enhances homologous recombination activity of hRAD51. Enhances homology-directed repair ~2 to 5-fold and increases CRISPR-mediated knock-in efficiencies in vitroandin vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 524.23 |
| 分子式 | C20H16Br2N2< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Songet al (2016) RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency. Nat.Commun. 7 10548. PMID: 26817820. Jayathilakaet al (2008) A chemical compound that stimulates the human homologous recombination protein RAD51. Proc.Natl.Acad.Sci.U.S.A. 105 15848. PMID: 18840682. |