| 货号 | 5116/50 |
| 别名 | N-(2,4-Dimethoxyphenyl)-N-(1-oxo-2- |
| 供应商 | Tocris |
| 生物活性 | Irreversible protein disulfide isomerase (PDI) inhibitor; inhibits growth of ovarian cancer cells. Suppresses tumor growth in a mouse xenograph model of human ovarian cancer. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 430.47 |
| 分子式 | C21H22N2O6 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Geet al (2013) Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase. ACS.Chem.Biol. 8 2577. PMID: 24070012. Xuet al (2012) Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. Proc.Natl.Acad.Sci.U.S.A. 109 16348. PMID: 22988091. |