货号 | 2429/50 |
别名 | α,α-Dimethyl-4-[1-hydroxy-4-[4-(hydro |
供应商 | Tocris |
生物活性 | Selective histamine H1 receptor antagonist (pKi = 8.1). Active metabolite of terfenadine that displays non-sedating antiallergic effects. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 538.12 |
分子式 | C32H39NO4.HCl |
可溶性/溶解性 | Soluble to 50 mM in DMSO |
CAS号 | 153439-40-8 |
参考文献 | Gillard and Chatelaine (2006) Changes in pH differently affect the binding properties of histamine H1 receptor antagonists. Eur.J.Pharmacol. 530 205. PMID: 16388798. Sakairiet al (2005) Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis. Pharmacology 75 76. PMID: 16037679. Markham and Wagstaff (1998) Fexofenadine. Drugs 55 269. PMID: 9506246. |