Tyrphostin B44, (-) enantiomer (50 MG)
货号:
0578/50 基本售价:
6236.2 元 规格:
50 mg
产品信息
概述货号 | 0578/50 |
别名 | (R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide |
性能供应商 | Tocris |
生物活性 | Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM), more active than the (+) enantiomer (Cat. No. 0579). Selective over ErbB2. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
计算分子量 | 308.34 |
分子式 | C18H16N2O3 |
可溶性/溶解性 | Soluble to 30 mM in DMSO |
CAS号 | 133550-32-0 |
参考文献 | Gazitet al (1991) Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrophostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J.Med.Chem. 34 1896. PMID: 1676428. |