JH-II-127
货号：
9632-25 基本售价：
6189.5 元 规格：
25mg
产品信息
概述| 货号 | 9632-25 |
| 描述 | JH-II-127 is a highly potent, selective, and cell-permeable LRRK2 inhibitor, with IC₅₀ of 6.6 nM, 2.2 nM ,47.7 nM for LRRK2-wild-type, LRRK2-G2019S, LRRK2-A2016T. JH-II-127 substantially inhibits Ser910 and Ser935 phosphorylation of both wild-type LRRK2 and G2019S mutant at a concentration of 0.1-0.3 μM in a variety of cell types and is capable of inhibiting Ser935 phosphorylation in mouse brain following oral delivery of doses as low as 30 mg/kg. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 外观 | Crystalline solid |
