PND-1186
货号：
2823-25 基本售价：
6189.5 元 规格：
25mg
产品信息
概述| 货号 | 2823-25 |
| 描述 | PND-1186 is a potent FAK (Focal adhesion kinase) inhibitor (IC₅₀ = 1.5 nM) with potential antineoplastic activity. PND-1186 inhibits FAK, blocks fibronectin-stimulated FAK autophosphorylation of Tyr397, and may prevent the integrin-mediated activation of several downstream signal transduction pathways, including ERK, JNK/MAPK and PI3K/Akt. This results in the reduction of the number of cancer stem cells (CSCs) and inhibits tumor cell migration, proliferation and survival. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 外观 | White to off-white solid |
