货号 | 2819-50 |
描述 | PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC₅₀ = 4 nM). PF-573,228 inhibits FAK phosphorylation on Tyr(397) with an IC₅₀ of 30-100 nM. Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro. |
供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | Off-white solid |