Letermovir
货号：
17556-10mg 基本售价：
6160.0 元 规格：
10 mg
产品信息
概述| 货号 | 17556-10mg |
| 描述 | Letermovir is a small molecule inhibitor of human cytomegalovirus viral replication (EC50 = ~5 nM with a selectivity index >15,000) that targets viral DNA cleavage and packaging.1,2 It functions to prevent viral DNA concatemers from forming the proper unit length and interferes with virion maturation.2 |
| 别名 | AIC246; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Marschall, M.,Stamminger, T.,Urban, A., et al. In vitro evaluation of the activities of the novel anticytomegalovirus compound AIC246 (letermovir) against herpesviruses and other human pathogenic viruses. Antimicrobial Agents and Chemotherapy 56(2), 1135-1137 (2012).
2.Goldner, T.,Hewlett, G.,Ettischer, N., et al. The novel anticytomegalovirus compound AIC246 (Letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase. Journal of Virology 85(20), 10884-10893 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 572.6 |
| 分子式 | C29H28F4N4O4 |
| CAS号 | 917389-32-3 |
| 稳定性 | ≥ 2 years |
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