MitoB-d15
货号:
17470-10mg 基本售价:
6160.0 元 规格:
10 mg
产品信息
概述货号 | 17470-10mg |
描述 | MitoB-d15 is intended for use as an internal standard for the quantification of MitoB (Item No. 17116) by GC- or LC-MS. MitoB is a ratiometric mass spectrometry probe that can be used for assessing changes in H2O2 within mitochondria in vivo. MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce a phenol product, MitoP (Item No. 17117).1,2 Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2concentration. |
性能供应商 | Cayman |
应用文献 |
1.Cochemé, H.M.,Logan, A.,Prime, T.A., et al. Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila. Nature Protocols 7(5), 946-958 (2012). 2.Cochemé, H.M.,Quin, C.,McQuaker, S.J., et al. Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix. Cell Metabolism 13(3), 340-350 (2011).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥99% deuterated forms (d1-d15) |
计算分子量 | 492.2 |
分子式 | C25H8D15BO2P • Br |
稳定性 | ≥ 2 years |
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