货号 | 16549-10mg |
描述 | α-Zearalenol is a major hepatic metabolite of zearalenone (Item No. 11353), a mycotoxin produced by fungi in food and animal feeds.1,2 It is a less potent agonist of estrogen receptors than the parent compound.3 However, α-zearalenol has pronounced effects on uterotropic activity, sperm motility, and preimplantation embryonic development.4,5,6 |
供应商 | Cayman |
应用文献 | |
1.Zinedine, A.,Soriano, J.M.,Moltó, J.C., et al. Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxin. Food and Chemical Toxicology 45, 1-18 (2007). 2.Ueno, Y. and Tashiro, F. α-Zearalenol, a major hepatic metabolite in rats of zearalenone, an estrogenic mycotoxin of Fusarium species. Journal of Biochemistry 89(2), 563-571 (1981). 3.Kiang, D.T.,Kennedy, B.J.,Pathre, S.V., et al. Binding characteristics of zearalenone analogs to estrogen receptors. Cancer Research 38(11 Pt 1), 3611-3615 (1978). 4.Mirocha, C.J.,Pathre, S.V.,Behrens, J., et al. Uterotropic activity of cis and trans isomers of zearalenone and zearalenol. Applied and Environmental Microbiology 35(5), 986-987 (1978). 5.Filannino, A.,Stout, T.A.E.,Gadella, B.M., et al. Dose-response effects of estrogenic mycotoxins (zearalenone, α- and β-zearalenol) on motility, hyperactivation and the acrosome reaction of stallion sperm. Reproductive Biology and Endocrinology 9, 1-10 (2011). 6.Wang, H.,Camargo Rodriguez, O. and Memili, E. Mycotoxin α-zearalenol impairs the quality of preimplantation porcine embryos. Journal of Reproduction and Development 58(3), 338-343 (2012). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 320.4 |
分子式 | C18H24O5 |
CAS号 | 36455-72-8 |
稳定性 | ≥ 2 years |
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