BW 245C
货号：
12050-10mg 基本售价：
6160.0 元 规格：
10 mg
产品信息
概述| 货号 | 12050-10mg |
| 描述 | BW 245C is a selective agonist for the DP1receptor.1,2 The Ki of BW 245C for the inhibition of [3H]-PGD2 binding to isolated human platelet membranes is 0.9 nM.1 It has a reported IC50 of 2.5 nM for the inhibition of ADP-induced human platelet aggregation3 and an IC50 of 250 nM for the inhibition of rat platelet aggregation.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Boie, Y.,Sawyer, N.,Slipetz, D.M., et al. Molecular cloning and characterization of the human prostanoid DP receptor. The Journal of Biological Chemisty 270, 18910-18916 (1995).
2.Town, M.H.,Casals-Stenzel, J., and Schillinger, E. Pharmacological and cardiovascular properties of a hydantoin derivative, BW 245 C, with high affinity and selectivity for PGD2 receptors. Prostaglandins 25, 13-28 (1983).
3.Narumiya, S., and Toda, N. Different responsiveness of prostaglandin D2-sensitive systems to prostaglandin D2 and its analogues. British Journal of Pharmacology 85, 367-375 (1985).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 368.5 |
| 分子式 | C19H32N2O5 |
| CAS号 | 72814-32-5 |
| 稳定性 | ≥ 1 year |
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