货号 | 16005-1g |
描述 | L-Selenomethionine (SeMet), a naturally occurring amino acid, is the predominant form of selenium found in Brazil nuts, grains, soy beans, and legumes.1 It promotes cell cycle progression and is known to elevate the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase, and glutathione peroxidase.2,3,4 At 5 µM, SeMet has been shown to selectively induce apoptosis in LNCaP prostate cancer cells without affecting non-cancerous cells.5 |
别名 | Selenomax®;SEM;SeMet; |
供应商 | Cayman |
应用文献 | |
1.Schrauzer, G.N. Selenomethionine: A review of its nutritional significance, metabolism and toxicity. Journal of Nutrition 130(7), 1653-1656 (2000). 2.Zeng, H. Selenite and selenomethionine promote HL-60 cell cycle progression. Journal of Nutrition 132(4), 674-679 (2002). 3.El-Sayed, W.M.,Aboul-Fadl, T.,Roberts, J.C., et al. Murine hepatoma (Hepa1c1c7) cells: A responsive in vitro system for chemoprotective enzyme induction by organoselenium compounds. Toxicol.In Vitro 21(1), 157-164 (2007). 4.Jornot, L. and Junod, A.F. Differential regulation of glutathione peroxidase by selenomethionine and hyperoxia in endothelial cells. Biochemistry Journal 306(Pt 2), 581-587 (1995). 5.Stewart, J.,Ware, J.,Boysen, C., et al. Effects of selenomethionine on the gene expression profile of cloned human prostate cancer cells representing a phenotypic continuum of cancer progression. Nutrition and Cancer 60(6), 826-836 (2008). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 196.1 |
分子式 | C5H11NO2Se |
CAS号 | 3211-76-5 |
稳定性 | ≥ 2 years |
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