| 货号 | 17878-10mg |
| 描述 | 1-Deoxynojirimycin (Item No. 10011718) is a glucose analog that potently inhibits α-glucosidase I and II. N-5-Carboxypentyl-1-deoxynojirimycin is a ligand used for the purification of glucosidase I and II.1,2 The carboxypentyl groups allows linkage of the inhibitor with resins for affinity chromatography.1,3 N-5-Carboxypentyl-1-deoxynojirimycin is at least as potent an inhibitor of glucosidase as 1-deoxynojirimycin (Kis = 0.45 and 2.1 µM, respectively, for pig liver glucosidase I).4 |
| 别名 | N-5-Carboxypentyl-1-dNM; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Bause, E.,Gross, A., and Schweden, J. N-Methyl-N-(5-carboxypentyl)-1-deoxynojirimycin, a new affinity ligand for the purification of trimming glucosidase I. FEBS Letters 278(2), 167-170 (1991). 2.Hentges, A., and Bause, E. Affinity purification and characterization of glucosidase II from pig liver. Biological Chemistry 378(9), 1031-1038 (1997). 3.Bernotas, R.C., and Ganem, B. Easy assembly of ligands for glycosidase affinity chromatography. Biochemistry Journal 270, 539-540 (1990). 4.Bause, E.,Schweden, J.,Gross, A., et al. Purification and characterization of trimming glucosidase I from pig liver. European Journal of Biochemistry 183, 661-669 (1989). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 277.3 |
| 分子式 | C12H23NO6 |
| CAS号 | 79206-51-2 |
| 稳定性 | ≥ 2 years |
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