PAD4 Inhibitor Screening Assay Kit (AMC)
货号：
701320-96Well 基本售价：
5950.0 元 规格：
96 wells
产品信息
概述| 货号 | 701320-96Well |
| 描述 | Protein arginine deiminase 4 (PAD4) is a guanidino-modifying enzyme that functions as a transcriptional coregulator catalyzing the conversion of specific arginine residues to citrulline. Substrates for PAD4 include histones H2A, H3, and H4. PAD4 autocitrullinates itself at several sites, inhibiting its enzymatic activity. PAD4 activity is increased in rheumatoid arthritis, producing an abundance of citrulline-containing proteins that generate an immune response resulting in production of autoantibodies that ultimately attack the host tissues. PAD4 has also been implicated in several other diseases including multiple sclerosis, Alzheimers disease, glaucoma, and cancer. Caymans PAD4 Inhibitor Screening Assay (AMC) provides a convenient, fluorescence-based method for screening human PAD4 inhibitors. |
| 别名 | PADI4;PADI5;PDI5;Peptidylarginine Deiminase 4;Protein Arginine Deiminase 4; |
性能| 供应商 | Cayman |
| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 稳定性 | ≥ 6 months |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
