PAD4 Autoantibody ELISA Kit
货号:
500930-96Well 基本售价:
5950.0 元 规格:
96 wells
产品信息
概述货号 | 500930-96Well |
描述 | Protein arginine deiminase 4 (PAD4) is a guanidino-modifying enzyme which catalyzes the conversion of specific arginine residues to citrulline in a calcium-dependent manner. PAD4 activity is increased in rheumatoid arthritis (RA), producing citrulline-containing proteins (CCP) that induce the formation of arthritogenic autoantibodies. In addition to anti-CCP autoantibodies, 23-45% of RA patients also produce autoantibodies specific for the PAD4 enzyme itself. Cayman’s PAD4 Autoantibody ELISA Kit is an immunometric assay which can be used to measure anti-PAD4 autoantibodies of any isotype (IgM, IgG, and IgA) in human plasma and serum without prior sample purification. Affinity-purified anti-PAD4 antibody isolated from the plasma of a patient with RA is used as the standard. One unit is approximately equal to 1 ng of anti-PAD4 Ig protein. The standard curve spans the range of 15.6-1,000 U/ml, with an LLOQ of 31.3 U/ml. |
别名 | PAD4 Autoantibody EIA Kit;PADI4;PADI5;PDI5;Peptidylartginine Deaminase 4;Protein Arginine Deiminase 4; |
性能供应商 | Cayman |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | 4 |
稳定性 | ≥ 1 year |
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