Histone H2A (Xenopus recombinant)
货号:
10261-1mg 基本售价:
5950.0 元 规格:
1 mg
产品信息
概述货号 | 10261-1mg |
描述 | A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around an octamer of histones.1 The octamer is composed of two of each histone H2A, H2B, H3, and H4. Histones H2A and H2B form a dimer. Histones H3 and H4 form a tetramer. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core.2 Histone H3 undergoes many modifications which include acetylation, phosphorylation, ubiquitylation, sumoylation, and biotinylation that are important for regulation of gene transcription.1 |
性能供应商 | Cayman |
应用文献 |
1.Bhaumik, S.R.,Smith, E. and Shilatifard, A. Covalent modifications of histones during development and disease pathogenesis. Nat. Struct. Mol. Biol. 14(11), 1008-1016 (2007). 2.Tanaka, Y.,Tawaramoto-Sasanuma, M.,Kawaguchi, S., et al. Expression and purification of recombinant human histones. Methods 33, 3-11 (2004).
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运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
纯度 | ≥95% estimated by SDS-PAGE |
稳定性 | ≥ 6 months |
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