Linsitinib, Free base
货号：
2294-25 基本售价：
5947.5 元 规格：
25mg
产品信息
概述| 货号 | 2294-25 |
| 描述 | A potent, small-molecule dual insulin-like growth factor-1 receptor (IGF-1R)/insulin receptor (IR) kinase inhibitor. Inhibits IGF-1R and IR kinases with IC₅₀ values of 35 nM and 75 nM, respectively. Linsitinib selectively blocks the autophosphorylation of both human IGF-1R and IR, inhibits the proliferation of a variety of tumor cell lines in vitro, and displays robust in vivo anti-tumor efficacy in an IGF-1R-driven xenograft model when administered orally. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20 ̊C |
| 外观 | White to off-white solid |
