| 货号 | 2510/50 |
| 别名 | 2-[[3-(Trifluoromethyl)phenyl]amino |
| 供应商 | Tocris |
| 生物活性 | Calcium-activated chloride channel (CaCC) (hCLCA1/mCLCA3) blocker; reduces mucin synthesis and release in cell culture and animal models. Possesses anti-inflammatory actions via inhibition of cyclooxygenases and inhibits Cl-/HCO3- exchanger activity. Increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 414.34 |
| 分子式 | C21H13F3N2O4 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| CAS号 | 66898-62-2 |
| 参考文献 | Walkeret al (2006) Talniflumate increases survival in a cystic fibrosis mouse model of distal intestinal obstructuve syndrome. J.Pharmacol.Exp.Ther. 317 275. PMID: 16354791. Knight (2004) Talniflumate (Genaera). Curr.Opin.Invest.Drugs 5557. Sanchezet al (1982) Action of a non-steroidal anti-inflammatory drug on gastric mucosa of rats. J.Appl.Toxicol. 242. |