SC 66 (50 MG)
货号:
4398/50 基本售价:
5938.8 元 规格:
50 mg
产品信息
概述货号 | 4398/50 |
别名 | (2E,6E)-2,6-Bis(4-pyridinylmethylene)cyclohexanone |
性能供应商 | Tocris |
生物活性 | Allosteric inhibitor of Akt; interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination. Exhibits anticancer activity in vitroandin vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 276.33 |
分子式 | C18H16N2O |
可溶性/溶解性 | Soluble to 75 mM in DMSO and to 75 mM in ethanol |
参考文献 | Joet al (2011) Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination. Proc.Natl.Acad.Sci.USA 108 6486. PMID: 21464312. |