货号 | 3864/50 |
别名 | 10,11-Dihydro-10-oxo-5H-dibenzo(Z)[ |
供应商 | Tocris |
生物活性 | Anticonvulsant; protects mice and rats against generalized tonic-clonic seizures induced by electroshock. Thought to act via inhibition of sodium channel activity. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 252.27 |
分子式 | C15H12N2O2 |
可溶性/溶解性 | Soluble to 50 mM in DMSO |
CAS号 | 28721-07-5 |
参考文献 | Zhenget al (2009) Oxcarbazepine, not its active metabolite, potentiates GABAA activation and aggravates absence seizures. Epilepsia 50 83. PMID: 18717705. Ambrosioet al (2002) Mechanism of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024. Neurochem.Res. 27 121. PMID: 11926264. Schmutzet al (1994) Oxcarbazepine: preclinical anticonvulsant profile and putative mechanism of action. Epilepsia 35 S47. PMID: 8039471. |