| 货号 | 0759/50 |
| 别名 | [1S-(1α,6β,7α,8β,8aβ)]-Octahydro-1,6,7,8 |
| 供应商 | Tocris |
| 生物活性 | Potent inhibitor of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 189.21 |
| 分子式 | C8H15NO4 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 100 mM in water |
| CAS号 | 79831-76-8 |
| 参考文献 | Gruterset al (1987) Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase. Nature 330 74. PMID: 2959866. Welkeret al (1987) Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine. Proc.Natl.Acad.Sci.U.S.A. 84 8120. PMID: 2825177. Saulet al (1984) Studies on the mechanism of castanospermine inhibition of α- and β-glucosidases. Arch.Biochem.Biophys. 230 668. PMID: 6424575. |