货号 | 0558/50 |
供应商 | Tocris |
生物活性 | 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM). |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 226.71 |
分子式 | C11H14N2O.HCl |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 78263-90-8 |
参考文献 | Glennonet al (2000) 2-substituted tryptamines: agents with selectivity for 5-HT6 serotonin receptors. J.Med.Chem. 43 1011. PMID: 10715164. Craiget al (1990) 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum. Naunyn Schmiedebergs Arch.Pharmacol. 342 9. PMID: 2402303. Ismaielet al (1990) 5-HT1 and 5-HT2 binding profiles of the serotonergic agents α-methyl serotonin and 2-methylserotonin. J.Med.Chem. 33 755. PMID: 2299641. Wilsonet al (1990) 5-Hydroxytryptamine3 receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 252 683. PMID: 1968974. |