| 货号 | 1316/1 |
| 别名 | (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,1 |
| 供应商 | Tocris |
| 生物活性 | Endogenous omega-3 fatty acid. Acts as a selective retinoid X receptor (RXR) agonist that displays no activity at RAR, thyroid hormone receptor or the vitamin D receptor (VDR). Activates all three RXR isoforms. Also shown to inhibit Aβ1-42 fibrillation and toxicity in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 328.49 |
| 分子式 | C106H175N35O24S4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 252198-49-5 |
| 参考文献 | Hossainet al (2009) Mechanism of docosahexaenoic acid-induced inhibition of in vitroAβ1-42 fibrillation and Aβ1-42-induced toxicity in SH-S5Y5 cells. J.Neurochem. 111 568. PMID: 19686246. Zapata-Gonzalezet al (2008) Human dendritic cell activities are modulated by the omega-3 fatty acid, docosahexaenoic acid, mainly through PPARγ: RXR heterodimers: comparison with other polyunsaturated fatty acids. J.Leukoc.Biol. 84 1172. PMID: 18632990. Mata de Urquniaet al (2000) Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science 290 2140. PMID: 11118147. |