| 货号 | 1851/1 |
| 别名 | GLP-1 (1-37) amide |
| 供应商 | Tocris |
| 生物活性 | Pancreatic hormone synthesized by post-translational processing of proglucagon. Unlike truncated forms of GLP-1, it has no effect on food intake in rats and does not enhance pancreatic insulin secretion. However it induces insulin expression in intestinal epithelial cells, which can restore glucose homeostasis when implanted into diabetic mice. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4169.52 |
| 分子式 | C186H275N51O59 |
| 可溶性/溶解性 | Soluble to 5 mg/ml in water |
| CAS号 | 87805-34-3 |
| 序列号 | HDEFERHAEGTFTSDVSSYLEGQAAKEFIA |
| 参考文献 | Suzukiet al (2003) Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells. Proc.Natl.Acad.Sci.USA 1005034. Navarroet al (1996) Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake. J.Neurochem. 67 1982. PMID: 8863504. Bellet al (1983) Exon duplication and divergence in the human preproglucagon gene. Nature 304 368. PMID: 6877358. |