| 货号 | 2084/1 |
| 别名 | Gastric |
| 供应商 | Tocris |
| 生物活性 | Potent insulinotropic hormone synthesized by duodenal K-cells. High affinity GIP receptor agonist (EC50 = 0.81 nM) that inhibits gastric acid secretion and stimulates pancreatic insulin release in response to glucose. Also affects lipid metabolism and displays mitogenic and antiapoptotic effects in pancreatic β-cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4983.58 |
| 分子式 | C226H338N60O66S |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 100040-31-1 |
| 序列号 | YAEGTFISDYSIAMDKIHQQDFVNWLLAQK |
| 参考文献 | Meieret al (2002) Gastric inhibitory polypeptide: the neglected incretin revisited. Regul.Peptides 1071. Trumperet al (2001) Glucose-dependent insulinotropic polypeptide is a growth factor for β (INS-1) cells by pleiotropic signaling. Mol.Endocrinol. 151159. Wheeleret al (1995) Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties. Endocrinol. 1364629. |