15-keto Prostaglandin A1
货号：
9000142-5mg 基本售价：
5824.0 元 规格：
5 mg
产品信息
概述| 货号 | 9000142-5mg |
| 描述 | Prostaglandin A1(PGA1) (Item No. 10010) was first isolated as a dehydration product of the PGE1 (Item No. 13010) compounds found in human semen.1 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase.2 It can be produced from PGA1 in pig lung, trachea, aorta, and pulmonary artery tissue preparations.2 15-keto PGA1, given at a concentration of 6 µM, causes vasoconstriction of rabbit lung that is comparable to that induced by angiotensin II.3 |
| 别名 | 15-keto PGA1; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Hamberg, M., and Samuelsson, B. Prostaglandins in human seminal plasma. The Journal of Biological Chemisty 241, 257-263 (1966).
2.Ody, C.,Dieterle, Y.,Wand, I., et al. PGA1 and PGF2α metabolism by pig pulmonary endothelium, smooth muscle, and fibroblasts. J.Appl.Physiol.Respir.Environ.Exerc.Physiol. 46(2), 211-216 (1979).
3.Gross, K.B., and Gillis, C.N. Comparison of the pulmonary vascular response to prostglandin A1, prostaglandin F2α and angiotensin II; metabolism of PGA1 in lung. Life Sciences 19(11), 1653-1661 (1976).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 334.5 |
| 分子式 | C20H30O4 |
| CAS号 | 61600-67-7 |
| 稳定性 | ≥ 1 year |
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