6β-Prostaglandin I1
货号:
18120-10mg 基本售价:
5712.0 元 规格:
10 mg
产品信息
概述货号 | 18120-10mg |
描述 | 6β 6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 µM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.1,2 |
别名 | 6β-PGI1;5,6β-dihydro PGI2; |
性能供应商 | Cayman |
应用文献 |
1.Whittle, B.J.R.,Moncada, S.,Whiting, F., et al. Carbacyclin - a potent stable prostacyclin analogue for the inhibition of platelet aggregation. Prostaglandins 19, 605-627 (1980). 2.Blair, I.A.,Hensby, C.N. and MacDermot, J. Prostacyclin-dependent activation of adenylate cyclase in a neuronal somatic cell hybrid: Prostanoid structure-activity relationships. British Journal of Pharmacology 69, 519-525 (1980).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥99% |
计算分子量 | 354.5 |
分子式 | C20H34O5 |
CAS号 | 62770-50-7 |
稳定性 | ≥ 2 years |
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