6α-Prostaglandin I1
货号：
18110-10mg 基本售价：
5712.0 元 规格：
10 mg
产品信息
概述| 货号 | 18110-10mg |
| 描述 | 6α-Prostaglandin I1(6α-PGI1) is a stable Prostaglandin I2(PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response.16α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml).2 |
| 别名 | 6α-PGI1;5,6α-dihydro PGI2; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Patrono, C.,Rotella, C.M.,Toccafondi, R.S., et al. Prostacyclin stimulates the adenylate cyclase system of human thyroid tissue. Prostaglandins 22(1), 105-115 (1981).
2.Whittle, B.J.R. and Moncada, S. Prostacyclin and its analogues for the therapy of thromboembolic disorders. Advances in Experimental Medicine and Biology 164, 193-209 (1984).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% |
| 计算分子量 | 354.5 |
| 分子式 | C20H34O5 |
| CAS号 | 62777-90-6 |
| 稳定性 | ≥ 2 years |
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